# InfoCoBuild

## Biostatistics and Design of Experiments

Biostatistics and Design of Experiments. Instructor: Prof. Mukesh Doble, Department of Biotechnology, IIT Madras. Biostatistics is the application of statistics to different topics in biology including medicine, pharmacy, public health science, agriculture and fishery. It involves the analysis of data from experiments; its interpretation and drawing conclusion from the results. It is very relevant to all UG and PG level degree programmes majoring in Biotechnology and allied fields as well as practicing scientists. It involves the application of statistical theory to real-world problems, the practice of designing and conducting biomedical experiments and clinical trials. Design of experiments is planning experimental strategy, screening a large number of parameters and selecting the important ones, determining the minimum number of experiments and deciding on the mode and manner in which experiment have to be conducted. The course encompasses topics such as distribution of data, sample size, tests of significance, data reduction, regression analysis, comparison of performance of drugs in clinical trials, design of experiments, screening and second order designs. (from nptel.ac.in)

 Introduction

 Lecture 01 - Introduction Lecture 02 - Experimental Design Strategy Lecture 03 - Data Types: Binomial Distribution Lecture 04 - Poisson Distribution Lecture 05 - Normal Distribution Lecture 06 - Standardized Normal Distribution, T-Distribution Lecture 07 - T-Distribution, Confidence Interval Lecture 08 - Statistical Tests Lecture 09 - T-Test Lecture 10 - T-Test: 2 Sample T-Test Examples Lecture 11 - Paired Sample T-Test Lecture 12 - F-Tests Lecture 13 - F-Tests (cont.) Lecture 14 - Analysis of Variance (ANOVA) Lecture 15 - ANOVA (cont.) Lecture 16 - ANOVA: Repeatability, Reproducibility Lecture 17 - ANOVA: Interactions Lecture 18 - ANOVA and Random or Mixed Effect Model Lecture 19 - 3 Way ANOVA: a Bioprocess Example, Latin Square Design Lecture 20 - 3 Way ANOVA with Interaction, Full Factorial Experimental Design Lecture 21 - Normality Test/Odds Ratio Lecture 22 - Chi Square Distribution Lecture 23 - Chi Square Distribution/Test Lecture 24 - Chi Square Test Lecture 25 - Chi Square Test and Weibull Distribution Lecture 26 - Weibull Distribution Lecture 27 - Weibull Distribution (cont.) Lecture 28 - Nonparametric Tests Lecture 29 - Nonparametric Tests, Homogeneity of Variance, Beta Distribution Lecture 30 - Exponential and Hypergeometric Distributions Lecture 31 - Hypergeometric and Log Normal Distributions Lecture 32 - Design of Experiments (DOE): Introduction Lecture 33 - Design of Experiments (DOE): Factorial Design Lecture 34 - Full Factorial Design Lecture 35 - Fractional Factorial Design Lecture 36 - Other Designs Lecture 37 - Second Order Designs Lecture 38 - Second Order Designs (cont.) Lecture 39 - Regression Analysis Lecture 40 - Control Charts

 References Biostatistics and Design of Experiments Instructor: Prof. Mukesh Doble, Department of Biotechnology, IIT Madras. Biostatistics is the application of statistics to different topics in biology including medicine, pharmacy, public health science, agriculture and fishery.