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Biomaterials for Bone Tissue Engineering Applications

Biomaterials for Bone Tissue Engineering Applications. Instructor: Prof. Bikramjit Basu, Materials Research Centre, IISc Bangalore. Biomaterials, recognized as a new class of materials in the Materials Science community, are being developed in last few decades for human health care. The design and development of biomaterials requires the integration of the concepts and expertise from two widely different disciplines, i.e. Materials Science & Engineering and Biological Science. This course will consist of several lectures on the basics of the cell biology and biomaterials science, followed by some case studies, illustrating various aspects of biomaterials development for orthopedic applications. The layout of this lecture series in terms of the succession of various concepts will primarily facilitate easier understanding for students and this important area of societal relevance in terms of human healthcare. (from nptel.ac.in)

Introduction


Introduction to Biomaterials and Biocompatibility
Lecture 01 - Introduction
Lecture 02 - Biomaterials
Lecture 03 - Biocompatibility
Lecture 04 - Biocompatibility and Host Response
Defining Tissue Engineering Scaffolds and Implants
Lecture 05 - Biological Cells
Lecture 06 - Cytoskeletal Structure, Cell Adaptation Processes, Protein
Lecture 07 - Bone Structure
Lecture 08 - Bone Properties
Lecture 09 - Fracture Toughness, Key Concepts of Biomaterials
Lecture 10 - Key Concepts of Biomaterials (cont.)
Structure and Properties of Proteins and Cells
Lecture 11 - Proteins
Lecture 12 - Cell Structure, Cell Signaling Process
Lecture 13 - Bacteria: Structure and Properties
Lecture 14 - Antibacterial Assays
Stem Cells and Cell Fate Processes
Lecture 15 - Cell Fate Processes; Cell Migration; Cell Division
Lecture 16 - Cell Differentiation, Polymerase Chain Reaction, Cell Death
Lecture 17 - Stem Cells
Lecture 18 - Stem Cell Differentiation
Cell-Material Interaction (In Vitro and In Vivo) and Clinical Trials
Lecture 19 - In Vivo Biocompatibility Assessment
Lecture 20 - In Vivo Biocompatibility (cont.)
Lecture 21 - Cell-Material Interaction
Lecture 22 - Cell Signaling
Lecture 23 - In Vitro Testing
Lecture 24 - Osteocalcin Assay, Immunofluorescence Assays
Lecture 25 - Biocompatibility Assay
Lecture 26 - Clinical Trials
Lecture 27 - Clinical Trials (cont.)
Manufacturing of Biomaterials (Metals, Ceramics and Polymers)
Lecture 28 - Basic Manufacturing Processes of Metallic Biomaterials
Lecture 29 - Fundamentals of the Ceramics Processing
Lecture 30 - Fundamentals of Polymers and Polymers Processing
Lecture 31 - Additive Manufacturing of Porous Scaffolds for Bone Tissue Engineering Applications
HA-based Composites
Lecture 32 - Osteoblast Cell Fate and High Toughness of Hydroxyapatite-Titanium Composites
Lecture 33 - Hydroxyapatite-based Multifunctional Composites for Bone Tissue Engineering Applications
Lecture 34 - Multifunctional HA-CaTiO3 Biocomposite for Bone Replacement Applications
Lecture 35 - Hydroxyapatite-Zinc Oxide Composites, Cell Fate and Antimicrobial
Lecture 36 - Synthesis, Antimicrobial and Cell Viability of Silver Doped Hydroxyapatites
Glass Ceramics for Orthopedic and Dental Applications, Acetabular Socket and Femoral Head
Lecture 37 - Processing and Properties of Dental Glass Ceramics
Lecture 38 - Biocompatibility of Sr-based Glass Ceramics
Lecture 39 - HDPE-HA-Alumina based Acetabular Socket for Total Hip Replacement Surgery
Lecture 40 - Near-net Shaped Ceramic Femoral Ball Head

References
Biomaterials for Bone Tissue Engineering Applications
Instructor: Prof. Bikramjit Basu, Materials Research Centre, IISc Bangalore. Biomaterials, recognized as a new class of materials in the Materials Science community, are being developed in last few decades for human health care.