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7.016 Introductory Biology

7.016 Introductory Biology (Fall 2018, MIT OCW). Instructors: Prof. Barbara Imperiali and Prof. Adam Martin. This course provides an introduction to fundamental principles of biochemistry, molecular biology, and genetics for understanding the functions of living systems. Taught for the first time in Fall 2013, this course covers examples of the use of chemical biology and twenty-first-century molecular genetics in understanding human health and therapeutic intervention. (from ocw.mit.edu)

Lecture 20 - Cell Signaling 1: Overview

Instructor: Prof. Barbara Imperiali. After completing the topic of protein trafficking, Professor Imperiali introduces cell signaling. In the first of two lectures on this topic, she covers the paradigms and mechanics of cell signaling.


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Lecture 01 - Introduction
Lecture 02 - Chemical Bonding and Molecular Interactions; Lipids and Membranes
Lecture 03 - Structures of Amino Acids, Peptides, and Proteins
Lecture 04 - Enzymes and Metabolism
Lecture 05 - Carbohydrates and Glycoproteins
Lecture 06 - Nucleic Acids
Lecture 07 - Replication
Lecture 08 - Transcription
Lecture 09 - Chromatin Remodeling and Splicing
Lecture 10 - Translation
Lecture 11 - Cells, the Simplest Functional Units
Lecture 12 - Genetics 1: Cell Division and Segregating Genetic Material
Lecture 13 - Genetics 2: Rules of Inheritance
Lecture 14 - Genetics 3: Linkage, Crossing Over
Lecture 15 - Genetics 4: The Power of Model Organisms in Biological Discovery
Lecture 16 - Recombinant DNA, Cloning and Editing
Lecture 17 - Genomes and DNA Sequencing
Lecture 18 - SNPs and Human Genetics
Lecture 19 - Cell Trafficking and Protein Localization
Lecture 20 - Cell Signaling 1: Overview
Lecture 21 - Cell Signaling 2: Examples
Lecture 22 - Neurons, Action Potential and Optogenetics
Lecture 23 - Cell Cycle and Checkpoints
Lecture 24 - Stem Cells, Apoptosis and Tissue Homeostasis
Lecture 25 - Cancer 1
Lecture 26 - Cancer 2
Lecture 27 - Visualizing Life: Dyes and Stains
Lecture 28 - Visualizing Life: Fluorescent Proteins
Lecture 29 - Cell Imaging Techniques
Lecture 30 - Immunology 1: Diversity, Specificity, and B Cells
Lecture 31 - Immunology 2: Memory, T Cells, and Autoimmunity
Lecture 32 - Infectious Disease, Viruses, and Bacteria
Lecture 33 - Bacteria and Antibiotic Resistance
Lecture 34 - Viruses and Antiviral Resistance
Lecture 35 - Reproductive Cloning and Embryonic Stem Cells