ME C117: Structural Aspects of Biomaterials

ME C117/BioEngineering: Structural Aspects of Biomaterials (Spring 2007, UC Berkeley). Instructor: Professor Lisa Pruitt. This course provides an overview of medical devices, FDA regulatory issues, biocompatibility and sterilization technology. It examines biomechanical properties: isotropy/anisotropy, stiffness, bending stresses, contact stresses, multiaxial loading, plasticity, fatigue, fracture, wear, corrosion, design issues. Also covered: orthopedics, dental, cardiovascular, and soft tissue reconstruction.

Course Overview

Lecture 01 - Course Overview
Lecture 02 - Biocompatibility/FDA Regulatory Agency
Lecture 03 - Orthopedics
Lecture 04 - Case Study: Sulzer Recall
Lecture 05 - Case Study: Hip Implant Corrosion
Lecture 06 - Final Project Outline
Lecture 07 - Case Study: Sterilization, oxidation, and aging in UHMWPE
Lecture 08 - Wear in Total Joint Replacements
Lecture 09 - Total Shoulder Replacements; Contact Stress
Lecture 10 - Contact Stress in Devices; Stress Shielding
Lecture 11 - Guest Lecture: Clinical Aspects of Orthopedic Surgery by Dr. Michael Ries
Lecture 12 - UHMWPE Fatigue
Lecture 13 - Fatigue Design
Lecture 14 - Guest Lecture: Spinal Implants by Dr. Andy Kohm
Lecture 15 - Defect Tolerant Philosophy
Lecture 16 - Guest Lecture: Fracture of Teeth Bone by Prof. Rob Ritchie
Lecture 17 - Dental Materials
Lecture 18 - Guest Lecture: Vascular Mechanics
Lecture 19 - In Class Demonstrations: Knee, Hip, Dental, Cardio
Lecture 20 - Guest Lecture: Stent Failure by Dr. Scott Robertson
Lecture 21 - Guest Lecture: Nitinol Device by Dr. Alan Pelton
Lecture 22 - Soft Tissue Reconstruction
Lecture 24 - Exam Solutions
Lecture 26 - Student Presentations
Lecture 27 - Student Presentations (cont.)