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Chemistry 203: Organic Spectroscopy

Chemistry 203: Organic Spectroscopy (Fall 2011, UC Irvine). These videos are part of a 28-lecture graduate-level course titled "Organic Spectroscopy" taught at UC Irvine by Professor James Nowick. The course covers infrared (IR) spectroscopy, mass spectrometry, and nuclear magnetic resonance (NMR) spectroscopy, the latter of which is the main focus. Topics covered in the NMR spectroscopy part of the course include chemical shifts, spin-spin coupling, dynamic effects in NMR spectroscopy, and 2D NMR spectroscopy (COSY, HMQC, HMBC, TOCSY, NOESY, ROESY).

Lecture 16 - The Importance of 13C Chemical Shifts in Structure and ...


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Lecture 01 - Infrared Spectroscopy: Introduction, Theory, Instrumentation, and Sample Preparation
Lecture 02 - Infrared Spectroscopy: C,H,O-Containing Functional Groups
Discussion 1 - Molecular Modeling with PyMOL
Lecture 03 - Effect of Ring Size Conjugation Electron-Withdrawing Groups
Lecture 04 - Mass Spectrometry: Theory, Instrumentation, and Techniques
Lecture 05 - Isotopic Masses, Isotopic Abundances, and High-Resolution Mass Spectrometry
Lecture 05A - Isotopic Masses, Isotopic Abundances, and High-Resolution Mass Spectrometry
Lecture 06 - Fragmentation in EIMS: Alkanes, Alkenes, Heteroatom Compounds, Carbonyl Compounds
Lecture 06A - Fragmentation in EIMS: Alkanes, Alkenes, Heteroatom Compounds, Carbonyl Compounds
Lecture 07 - Introduction to NMR Spectroscopy: Concepts and Theory, Part 1
Lecture 08 - Introduction to NMR Spectroscopy: Concepts and Theory, Part 2
Lecture 09 - Chemical Shift. 1H NMR Chemical Shifts
Lecture 10 - 13C NMR Chemical Shifts. Chemical Equivalence and Spin-Spin Coupling
Lecture 11 - Magnetic Equivalence, Spin Systems, and Pople Notation
Lecture 12 - Coupling Analysis in First-Order and Near-First-Order Systems
Lecture 13 - Coupling Analysis in First-Order and Near-First-Order Systems (cont.)
Lecture 14 - Spin-Spin Coupling in Stereochemistry and Structure Determination
Lecture 15 - Coupling Involving Other Nuclei
Lecture 16 - The Importance of 13C Chemical Shifts in Structure and Stereochemistry Determination
Lecture 17 - Introduction to 2D NMR Spectroscopy
Lecture 18 - Dynamic Effects in NMR Spectroscopy
Lecture 19 - The Nuclear Overhauser Effect in Stereochemistry and Structure Determination
Lecture 20 - Understanding Complex Pulse Sequences
Lecture 21 - Using HMBC to Help Solve Structures: "Putting the Pieces Together"
Lecture 22 - Aspects of COSY, HMQC, HMBC, and Related Experiments
Lecture 23 - Using TOCSY to Elucidate Spin Systems. ROESY
Lecture 24 - Using Organic Spectroscopy to Solve Complex Structures
Lecture 25 - INADEQUATE. Some Thoughts on Homework Set 9
Lecture 26 - Using Organic Spectroscopy to Solve Complex Structures, Part 2
Lecture 27 - Using HMQC-TOCSY or HSQC-TOCSY to Deal with Overlap
Lecture 28 - Some Other Useful NMR Techniques