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Organometallic Chemistry

Organometallic Chemistry. Instructor: Prof. Debabrata Maiti, Department of Chemistry, IIT Bombay. The basic principles of organometallic chemistry will be discussed in this course. The modern chemistry is merged into one from classical organic chemistry and traditional inorganic chemistry. We will shed light on activation of small molecule by metal-ligand complex. We will discuss the stepwise mechanism of insertion of metal into organic molecules and elimination by different pathway. Only catalytic amount of metal can produce the large number of molecules those include drug, natural products, pharmaceuticals, our daily needs, etc. in gigantic quantity. (from nptel.ac.in)

Lecture 15 - External Attack by a Ligand and Reductive Coupling

Substitution reactions are generally occurred by replacement of one ligand with another one. Substitution of one ligand is depends on electron properties and steric properties of both incoming and outgoing ligand. Two ligands in a given organometallic complex are coupled to produce the new compound via reductive elimination.


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Lecture 01 - Introduction to Organometallic Chemistry
Lecture 02 - Counting of Electrons
Lecture 03 - Ligand Substitution Reactions
Lecture 04 - Oxidative Addition: Concerted Mechanism
Lecture 05 - Oxidative Addition: SN2 Mechanism
Lecture 06 - Oxidative Addition: Radical Mechanism
Lecture 07 - Reductive Elimination
Lecture 08 - Migratory Insertion and Elimination Reactions
Lecture 09 - Migration and Insertion Reactions
Lecture 10 - Alpha-Migratory Insertion and Alpha-Elimination Reactions
Lecture 11 - Beta-Migratory Insertion
Lecture 12 - Beta-Elimination Reaction
Lecture 13 - Alpha-Abstraction and Beta-Abstraction
Lecture 14 - 4-Center Reactions; [2+2] Reactions
Lecture 15 - External Attack by a Ligand and Reductive Coupling
Lecture 16 - Hydrogenation Reaction
Lecture 17 - Hydrogenation Reaction: Dihydride Catalyst
Lecture 18 - Stereoselective Hydrogenation Reaction
Lecture 19 - Carbonylation Reaction: Monsanto Acetic Acid Process, Hydroformylation
Lecture 20 - Carbonylation Reaction: Hydroformylation, Hydrocarboxylation, Hydrocyanation