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Fruits of the Genome Sequences

Fruits of the Genome Sequences: Dr. Botstein gives an overview of the benefits for science and society derived from sequencing the genomes of multiple organisms, including humans. The sequences show that many genes have been conserved during evolution; a finding that allows scientists to study simple organisms such as yeast and relate their findings to mammalian biology. In addition, mining genome sequences has identified numerous genes involved in human disease, in some cases resulting in improved screening and treatment.

Connecting Growth Control and Stress Response: Botstein describes experiments done in his lab studying, in yeast, the coordination of growth rate, stress response, metabolism and cell division. Using innovative methods to color code and cluster numerical data from DNA hybridization experiments allows the identification of genes involved in regulating how fast cells grow under different conditions.

David Botstein served as the director of the Lewis-Sigler Institute for Integrative Genomics at Princeton University from 2003?2013, where he remains an Anthony B. Evnin Professor of Genomics. (from ibiology.org)

1. Fruits of the Genome Sequences
Dr. Botstein gives an overview of the benefits for science and society derived from sequencing the genomes of multiple organisms, including humans.

2. Connecting Growth Control and Stress Response
Botstein describes experiments done in his lab studying, in yeast, the coordination of growth rate, stress response, metabolism and cell division.


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