InfoCoBuild

Living Together: The Symbiosis of Host-microbial Interactions

Living together: The Symbiosis of Host-microbial Interactions: Advances in rRNA sequencing and other techniques have allowed scientists to characterize novel symbiotic partnerships. Dr. Margaret McFall-Ngai provides an overview of the three main types of symbiosis: mutualism (both partners benefit), commensalism (only one partner benefits), and parasitism (one partner benefits, but the other partner is harmed). McFall-Ngai's research is currently focused on understanding the establishment and maintenance of symbiotic relationships, and the molecular effects that these relationships have on development, health, and disease.

The Hawaiian Bobtail Squid - Vibrio Fischeri Association: McFall-Ngai tells the story of a symbiosis between the Hawaiian bobtail squid and Vibrio fischeri (V. fischeri), a type of luminescent bacteria that enables the squid to hunt at night. McFall-Ngai and collaborators have identified the molecular mechanism by which nascent Hawaiian bobtail squid select V. fischeri from the thousands of other bacteria in their habitat. V. fischeri induces developmental changes in the squid that drive daily rhythms of gene expression, which are necessary to control bacterial growth, a crucial cycle in this symbiotic partnership.

Dr. Margaret McFall-Ngai is a Professor and Director of the Pacific Biosciences Research Center at the University of Hawaii Manoa. (from ibiology.org)

1. Living together: The Symbiosis of Host-microbial Interactions
Dr. Margaret McFall-Ngai provides an overview of the three main types of symbiosis: mutualism (both partners benefit), commensalism (only one partner benefits), and parasitism (one partner benefits, but the other partner is harmed).

2. The Hawaiian Bobtail Squid - Vibrio Fischeri Association
McFall-Ngai tells the story of a symbiosis between the Hawaiian bobtail squid and Vibrio fischeri (V. fischeri), a type of luminescent bacteria that enables the squid to hunt at night.


Related Links
Microbial Diversity and Evolution
Microbes are diverse, ancient, numerous and ubiquitous. Dianne Newman gives an overview of these four key points. She presents mind-boggling data on the numbers of microbes inhabiting the earth, ...
The Evolving Human Microbiome
Dr. Alexander Khoruts, MD, of the University of Minnesota's Microbiota Therapeutics Program, describes the symbiotic relationships humans have with the specialized microbial communities that inhabit our bodies.
Virology
The course will emphasize the common reactions that must be completed by all viruses for successful reproduction within a host cell and survival and spread within a host population.
Microbial Genomics and Genetics
This course emphasizes bacterial and archaeal genetics and comparative genomics. Genetics and genomic methods used to dissect metabolic and development processes in bacteria, archaea, and selected microbial eukaryotes.