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Chemistry 128: Introduction to Chemical Biology

Chemistry 128: Introduction to Chemical Biology (Winter 2013, UC Irvine). Instructor: Professor Gregory Alan Weiss. Chemistry 128 provides an introduction to the basic principles of chemical biology: structures and reactivity; chemical mechanisms of enzyme catalysis; chemistry of signaling, biosynthesis, and metabolic pathways.

Lecture 04 - Combinatorial Chemistry and Biology

Time Lecture Chapters
[00:28:06] 1. MO Theory
[00:32:32] 2. Do Not Use Curved Arrows for Hydrogen Bonds
[00:34:00] 3. The Molecules of Life on Earth
[00:37:40] 4. Chemistry of CN
[00:50:27] 5. Formation of DAMN
[00:53:32] 6. Prebiotic Synthesis
[01:06:29] 7. Oligomers of Nucleotide Subunits
[01:08:00] 8. The RNA World
[01:09:19] 9. Synthesis of Amino Acids
[01:12:35] 10. Non-Covalent Interactions Dominate Biology
[01:16:35] 11. Charge-Charge Interactions

Go to the Course Home or watch other lectures:

Lecture 01 - Introduction/What is Chemical Biology?
Lecture 02 - Common Tools in Chemical Biology
Lecture 03 - Reactivity and Arrow Pushing
Lecture 04 - Combinatorial Chemistry and Biology
Lecture 05 - Non-Covalent Interactions, DNA
Lecture 06 - DNA Reactivity with Small Molecules
Lecture 07 - DNA, RNA, and Cancer
Lecture 08 - RNA
Lecture 09 - RNA part 2
Lecture 10 - Proteins and Amino Acid Conformations
Lecture 11 - Proteins and Amino Acid Conformations, Part 2
Lecture 12 - Protein Functions
Lecture 13 - Protein Function and Enzymes
Lecture 14 - Glycobiology
Lecture 15 - Glycobiology and Polyketides
Lecture 16 - Glycobiology and Polyketides, Part 2
Lecture 17 - Terpenes and Cell Signaling, Part 1
Lecture 18 - Terpenes and Cell Signaling, Part 2