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Chemistry 128: Introduction to Chemical Biology

Chemistry 128: Introduction to Chemical Biology (Winter 2013, UC Irvine). Instructor: Professor Gregory Alan Weiss. Chemistry 128 provides an introduction to the basic principles of chemical biology: structures and reactivity; chemical mechanisms of enzyme catalysis; chemistry of signaling, biosynthesis, and metabolic pathways.

Lecture 11 - Proteins and Amino Acid Conformations, Part 2

Time Lecture Chapters
[00:28:13] 1. Amino Acids and Proteins
[00:30:53] 2. a-Helices Form a Dipole
[00:31:09] 3. B-Sheets Come in Two Flavors
[00:34:39] 4. Secondary Structure - Backbone, Conformations
[00:44:40] 5. Conformational Analysis for the Cognoscente (White Board)
[00:58:07] 6. Amino Acids Examples (White Board)
[01:05:01] 7. Conformations to Watch For
[01:09:38] 8. Allylic Strain Dominates the Protein Backbone
[01:13:10] 9. Disulfide Bonds in Proteins
[01:15:34] 10. Protein Structure
[01:17:50] 11. All a-Helical Proteins

Go to the Course Home or watch other lectures:

Lecture 01 - Introduction/What is Chemical Biology?
Lecture 02 - Common Tools in Chemical Biology
Lecture 03 - Reactivity and Arrow Pushing
Lecture 04 - Combinatorial Chemistry and Biology
Lecture 05 - Non-Covalent Interactions, DNA
Lecture 06 - DNA Reactivity with Small Molecules
Lecture 07 - DNA, RNA, and Cancer
Lecture 08 - RNA
Lecture 09 - RNA part 2
Lecture 10 - Proteins and Amino Acid Conformations
Lecture 11 - Proteins and Amino Acid Conformations, Part 2
Lecture 12 - Protein Functions
Lecture 13 - Protein Function and Enzymes
Lecture 14 - Glycobiology
Lecture 15 - Glycobiology and Polyketides
Lecture 16 - Glycobiology and Polyketides, Part 2
Lecture 17 - Terpenes and Cell Signaling, Part 1
Lecture 18 - Terpenes and Cell Signaling, Part 2