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Chemistry 128: Introduction to Chemical Biology

Chemistry 128: Introduction to Chemical Biology (Winter 2013, UC Irvine). Instructor: Professor Gregory Alan Weiss. Chemistry 128 provides an introduction to the basic principles of chemical biology: structures and reactivity; chemical mechanisms of enzyme catalysis; chemistry of signaling, biosynthesis, and metabolic pathways.

Lecture 10 - Proteins and Amino Acid Conformations

Time Lecture Chapters
[00:19:40] 1. RNA
[00:22:14] 2. Proteins: of Primary Importance
[00:28:38] 3. Peptides and Protein are Directional
[00:32:39] 4. Useful to Know: pKa Values
[00:35:14] 5. Amino Acid Sidechains Dictate Protein Folding and Protein-Protein Interactions
[00:42:05] 6. Peptides Can Make Effective Drugs
[00:49:29] 7. Chemical Synthesis of Peptides and Proteins
[00:59:51] 8. Protein Splicing to Remove Inteins
[01:04:31] 9. Protein Structure: The Sum of Lots of Little Forces
[01:15:10] 10. a-Helices Form a Dipole

Go to the Course Home or watch other lectures:

Lecture 01 - Introduction/What is Chemical Biology?
Lecture 02 - Common Tools in Chemical Biology
Lecture 03 - Reactivity and Arrow Pushing
Lecture 04 - Combinatorial Chemistry and Biology
Lecture 05 - Non-Covalent Interactions, DNA
Lecture 06 - DNA Reactivity with Small Molecules
Lecture 07 - DNA, RNA, and Cancer
Lecture 08 - RNA
Lecture 09 - RNA part 2
Lecture 10 - Proteins and Amino Acid Conformations
Lecture 11 - Proteins and Amino Acid Conformations, Part 2
Lecture 12 - Protein Functions
Lecture 13 - Protein Function and Enzymes
Lecture 14 - Glycobiology
Lecture 15 - Glycobiology and Polyketides
Lecture 16 - Glycobiology and Polyketides, Part 2
Lecture 17 - Terpenes and Cell Signaling, Part 1
Lecture 18 - Terpenes and Cell Signaling, Part 2