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Chemistry 128: Introduction to Chemical Biology

Chemistry 128: Introduction to Chemical Biology (Winter 2013, UC Irvine). Instructor: Professor Gregory Alan Weiss. Chemistry 128 provides an introduction to the basic principles of chemical biology: structures and reactivity; chemical mechanisms of enzyme catalysis; chemistry of signaling, biosynthesis, and metabolic pathways.

Lecture 16 - Glycobiology and Polyketides, Part 2

Time Lecture Chapters
[00:00:00] 1. Polysaccharides
[00:08:45] 2. Fatty Acid Synthase: Paradigm for a Polyketide Synthesis Machine
[00:10:58] 3. Plasma Membrane = Lipid Barrier
[00:13:44] 4. Hydrolysis of Lipids in Cell Signaling
[00:15:26] 5. Prostaglandin Signaling to Coordinate Cell Response
[00:16:15] 6. Leukotrienes Mediate Inflammatory Response
[00:19:09] 7. Shutting Down the Prostaglandin Pathway at its Start
[00:23:39] 8. Converting Fats into Soaps
[00:25:54] 9. Diversifying Products from Polyketide Synthases
[00:39:54] 10. Fatty Acid Synthase (FAS) Has a Circular Assembly Line
[00:44:18] 11. Terpenes: Built from Isoprene (5C) Units
[00:56:18] 12. Inhibition of Cholesterol Synthesis
[00:57:48] 13. Cyclization of Straight-Chain Precursors by Enzymes

Go to the Course Home or watch other lectures:

Lecture 01 - Introduction/What is Chemical Biology?
Lecture 02 - Common Tools in Chemical Biology
Lecture 03 - Reactivity and Arrow Pushing
Lecture 04 - Combinatorial Chemistry and Biology
Lecture 05 - Non-Covalent Interactions, DNA
Lecture 06 - DNA Reactivity with Small Molecules
Lecture 07 - DNA, RNA, and Cancer
Lecture 08 - RNA
Lecture 09 - RNA part 2
Lecture 10 - Proteins and Amino Acid Conformations
Lecture 11 - Proteins and Amino Acid Conformations, Part 2
Lecture 12 - Protein Functions
Lecture 13 - Protein Function and Enzymes
Lecture 14 - Glycobiology
Lecture 15 - Glycobiology and Polyketides
Lecture 16 - Glycobiology and Polyketides, Part 2
Lecture 17 - Terpenes and Cell Signaling, Part 1
Lecture 18 - Terpenes and Cell Signaling, Part 2