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Chemistry 128: Introduction to Chemical Biology

Chemistry 128: Introduction to Chemical Biology (Winter 2013, UC Irvine). Instructor: Professor Gregory Alan Weiss. Chemistry 128 provides an introduction to the basic principles of chemical biology: structures and reactivity; chemical mechanisms of enzyme catalysis; chemistry of signaling, biosynthesis, and metabolic pathways.

Lecture 15 - Glycobiology and Polyketides

Time Lecture Chapters
[00:00:00] 1. Carbohydrates
[00:03:15] 2. Glycosylated Proteins
[00:07:25] 3. Extending Oligosaccharides one Monomer at a Time
[00:08:26] 4. More Knee Join Oligosaccharides
[00:10:25] 5. Snot and Mucus: Anionic Polysaccharides
[00:13:21] 6. N-Linked Glycosides: Added as Complex Oligosaccharides
[00:22:56] 7. What is the Function of Glycosylation?
[00:25:37] 8. Cell Culture Production of Proteins
[00:27:54] 9. Glucuronidation Used to Designate Small Molecules for Excretion
[00:29:49] 10. Glucose Homeostasis
[00:31:39] 11. Non-Enzymatic Glycosylation
[00:35:29] 12. Sweeteners: Taste Good for the Calories
[00:41:00] 13. Terpenes and Polyketides
[00:45:09] 14. Nature Prefers Thioesters for the Claisen
[00:48:06] 15. Rapid Exchange of Thioesters
[00:49:28] 16. Fatty Acid Synthesis by Polyketide

Go to the Course Home or watch other lectures:

Lecture 01 - Introduction/What is Chemical Biology?
Lecture 02 - Common Tools in Chemical Biology
Lecture 03 - Reactivity and Arrow Pushing
Lecture 04 - Combinatorial Chemistry and Biology
Lecture 05 - Non-Covalent Interactions, DNA
Lecture 06 - DNA Reactivity with Small Molecules
Lecture 07 - DNA, RNA, and Cancer
Lecture 08 - RNA
Lecture 09 - RNA part 2
Lecture 10 - Proteins and Amino Acid Conformations
Lecture 11 - Proteins and Amino Acid Conformations, Part 2
Lecture 12 - Protein Functions
Lecture 13 - Protein Function and Enzymes
Lecture 14 - Glycobiology
Lecture 15 - Glycobiology and Polyketides
Lecture 16 - Glycobiology and Polyketides, Part 2
Lecture 17 - Terpenes and Cell Signaling, Part 1
Lecture 18 - Terpenes and Cell Signaling, Part 2