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Chemistry 128: Introduction to Chemical Biology

Chemistry 128: Introduction to Chemical Biology (Winter 2013, UC Irvine). Instructor: Professor Gregory Alan Weiss. Chemistry 128 provides an introduction to the basic principles of chemical biology: structures and reactivity; chemical mechanisms of enzyme catalysis; chemistry of signaling, biosynthesis, and metabolic pathways.

Lecture 08 - RNA

Time Lecture Chapters
[00:00:00] 1. Announcements
[00:18:00] 2. DNA Chemistry and Cancer
[00:21:00] 3. RNA: Soldier, Sailor, Tinker, Spy
[00:22:40] 4. Differences Between RNA and DNA
[00:23:25] 5. RNA Hydrolysis
[00:27:27] 6. RNase Mechanism of Action
[00:30:38] 7. How to Shut Down a Very Effective Enzyme
[00:33:25] 8. The 5-Methyl Group of Thymine Provides a Chemical Code for DNA
[00:36:35] 9. RNA Bases can Be Modified
[00:38:14] 10. RNA Adopts Globular Structures
[00:40:14] 11. Systemizing Structure in RNA
[00:46:20] 12. RNA Polymerase
[00:50:40] 13. DNA Primase
[00:52:27] 14. Transcription in Action
[01:15:32] 15. The Yeast Two-Hybrid System Allows in Cell Testing for Binding
[01:17:53] 16. Comparing Bacterial and Eukaryotic mRNA Factors

Go to the Course Home or watch other lectures:

Lecture 01 - Introduction/What is Chemical Biology?
Lecture 02 - Common Tools in Chemical Biology
Lecture 03 - Reactivity and Arrow Pushing
Lecture 04 - Combinatorial Chemistry and Biology
Lecture 05 - Non-Covalent Interactions, DNA
Lecture 06 - DNA Reactivity with Small Molecules
Lecture 07 - DNA, RNA, and Cancer
Lecture 08 - RNA
Lecture 09 - RNA part 2
Lecture 10 - Proteins and Amino Acid Conformations
Lecture 11 - Proteins and Amino Acid Conformations, Part 2
Lecture 12 - Protein Functions
Lecture 13 - Protein Function and Enzymes
Lecture 14 - Glycobiology
Lecture 15 - Glycobiology and Polyketides
Lecture 16 - Glycobiology and Polyketides, Part 2
Lecture 17 - Terpenes and Cell Signaling, Part 1
Lecture 18 - Terpenes and Cell Signaling, Part 2